Two men are being questioned by police over the stabbing death of a 26-year-old man at the Esplanade train station in the early hours of January 27.
A police spokeswoman said the 19-year-old men were being held in custody on Thursday while they assisted police with their enquiries into a brawl which took place near the train station about 3.30am.
During the brawl, the victim was critically injured and later died at Royal Perth Hospital.
St John Ambulance said the patient was found unconscious with no pulse, with wounds to his left shoulder and the left side of his head.